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Decipher Prostate Genomic Classifier

Decipher Prostate is a tissue-based genomic test that provides actionable information for physicians and their patients to make treatment decisions across the spectrum of localized prostate cancer.

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Watch this video to learn more about the Decipher Prostate test, which can bring clarity and confidence to you and your physician during treatment planning.

What is Decipher Prostate?

  • Decipher Prostate is a tissue-based genomic test that provides important information about the underlying biology of your tumor.
  • Testing is performed on existing prostate tissue from either your biopsy or radical prostatectomy (surgery to remove the prostate).
    No additional medical procedure is required.
  • Decipher Prostate examines the expression of 22 genes that can help identify tumors that are more likely to spread outside the prostate.
  • The results reports your Decipher risk score (from 0.0 to 1.0).
    A lower score reflects a less aggressive tumor, while
    a higher score reflects a more aggressive tumor.
  • Speak with your physician to see if Veracyte’s Decipher Prostate Genomic Classifier is appropriate for you.

How Decipher Prostate Fits into the Prostate Cancer Patient Journey

How Do Physicians Assess Patient Risk in Prostate Cancer?

  • Physicians typically estimate a patient’s risk of their prostate cancer spreading by several factors that include: how aggressive the cancer looks under the microscope (Gleason Score), the amount of cancer in the prostate (imaging), and the result of their prostate-specific antigen (PSA) blood test.
  • This information is used to place the patient into a risk group (very low, low, favorable intermediate, unfavorable intermediate, high, and very high) and help identify appropriate treatment options.
  • Key questions such as who to treat, when to treat, and how much to treat are not always clear based on these factors alone. Sometimes, more information is needed to determine the best treatment plan.

What is Tumor Genomic Testing?

Tumor genomic testing is the study of the activity of genes in a tumor. It tells us which genes are being used by the tumor to help it grow and spread. This information can be used by your doctor to help personalize your cancer treatment by helping to determine the type and intensity of treatment best suited to the tumor you have.

Decipher Prostate can be performed on tissue
collected at biopsy. Click the link to view the video explaining the Decipher Prostate Biopsy test report.


Decipher Prostate can be performed on tissue
collected after surgery. Click the link to view the video explaining the Decipher Prostate RP test report.

My Physician has Ordered Decipher Testing

If your physician has already ordered Decipher testing, it is being processed and the test report will be delivered to your physician upon the completion of the genomic analysis. For any questions regarding Decipher testing, please discuss with your physician or contact Client Services at [email protected].

Physician orders
Decipher

Decipher handles tissue collections, processing, and analysis as well as billing to insurance

Decipher report is generated and sent to ordering physician

Is Decipher Prostate Covered by Medicare and Commercial Insurance?

Decipher Prostate is covered by Medicare for all beneficiaries with localized prostate cancer

Decipher Prostate is included in national guidelines and covered by major commercial insurance plans throughout the US

Financial support may be available to eligible patients via the Decipher Assist Program

Decipher Prostate Patient Resources

Decipher Prostate Patient Brochure

Decipher Assist Form

Decipher Prostate Patient Video

Don’t see what you’re looking for?

Visit these pages for more information or leave us a message on the contact form.

Frequently Asked Questions

How can the Decipher Prostate or Decipher Bladder test be ordered?

The Decipher Prostate Genomic Classifier must be ordered by the physician treating the patient.

What is tumor genomic testing?

Tumor genomic testing is the study of the activity of genes in a tumor. It tells us which genes are being used by the tumor to help it grow and spread. This information can be used by your doctor to help personalize your cancer treatment by helping to determine the type and intensity of treatment best suited to the tumor you have.

Who can I speak to if I have questions about billing?

We are committed to ensuring access to all eligible patients. Click here for more information about our Decipher Assist Program.
For questions related to billing and insurance, please reach out to Veracyte’s billing team at [email protected] or call us at 1.888.792.1601 (select option #3).

What does my Decipher Prostate test report look like?

The first page of the test report includes the patient’s Decipher Score, Decipher risk group (low, intermediate, or high), interpretation language, and risk estimates of prostate cancer specific outcomes. The second page contains more detailed information relevant to the specific patient. Click here to view a tutorial about the Decipher Prostate Biopsy and RP reports.

How do I get a copy of my test result? 

Your Decipher report may be requested from your physician. If you have questions, please email [email protected]

Is the Decipher Prostate Genomic Classifier or Decipher Bladder Genomic Classifier FDA cleared?  

The Decipher Prostate Genomic Classifier and the Decipher Bladder Genomic Classifier are available as part of Veracyte’s Clinical Laboratory Improvement Amendments (CLIA)-validated laboratory developed test (LDT) service. FDA approval or clearance is not required for the Decipher Prostate Genomic Classifier or Decipher Bladder Genomic Classifier.

Veracyte Labs SD, which performs Decipher testing is accredited/licensed by the following:

  • College of American Pathologists
  • Centers for Medicare and Medicaid Services (CMS) CLIA
  • California Department of Public Health
  • New York State Department of Health
  • Pennsylvania Department of Health
  • State of Rhode Island and Providence Plantations Department of Health Center for Health Facilities Regulation
  • Maryland Department of Health, Office of Health Care Quality
Can the Decipher Prostate Genomic Classifier or Decipher Bladder Genomic Classifier be ordered if I live outside the United States?

Currently, Decipher testing is only available within the United States. Decipher testing is available as part of Veracyte’s CLIA-validated laboratory developed test (LDT) service. Veracyte’s exclusive global access to the nCounter Analysis System for diagnostic testing will allow us to make our genomic classifiers – currently performed in our centralized labs for patients in the U.S. – available to physicians and their patients globally. We plan to adapt Decipher genomic testing to the nCounter Analysis System in the next few years. Feel free to fill out our contact us form should you be interested in Decipher testing outside the United States. 

How Can We Help

Please leave a message and a representative from our client services team will reach out shortly to help answer your questions.

Decipher Genomic Testing is available only through a physician’s order. Talk to your doctor about whether Decipher might be right for you.

Contact Details

Available between 8AM to 5PM PST

Call us at:

1.888.792.1601
1.858.766.6575 (fax)

Customer service inquiries:

[email protected]

Billing inquiries:

[email protected]
1.888.792.1601 (option 3)